The general utility of the folding strain control concept for remote stereocontrol has been examined in the ring closure reaction of 2-(6′-trimethylsilylhex-4′-enyl)cyclohex-2-enones with various alkyl-substituted side chains.
T. Tokoroyama, K. Okada and H. Iio, J. Chem. Soc., Chem. Commun., 1989, 1572 DOI: 10.1039/C39890001572
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