Selenium-induced cyclofunctionalisation of allylic O-methyl isoureas: synthesis of imidazolines (4,5-dihydroimidazoles) and 5,6-dihydro-1,3-oxazines
Abstract
Imidazolines are prepared by treatment of allylic O-methyl isoureas with phenylseleneyl chloride in the presence of silica gel; when the organoselenium-mediated cyclisation is performed with phenylselenenyl trifluoromethanesulphonate and trifluoromethanesulphonic acid 5,6-dihydro-1,3-oxazines are obtained.