Issue 7, 1989

Bromination of N-phthaloylamino acid derivatives

Abstract

Hydrogen transfer to the bromine atom from the α-position of N-phthaloylamino acid derivatives is disfavoured to such an extent that bromination of N-phthaloyl derivatives of valine and phenylalanine occurs regiospecifically at the β-position, while halogenation of N-phthaloyl derivatives of glycylglycine and glycylglycylvaline occurs selectively at the C-terminal and non-terminal glycine residues, respectively.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1989, 385-386

Bromination of N-phthaloylamino acid derivatives

C. J. Easton, E. W. Tan and M. P. Hay, J. Chem. Soc., Chem. Commun., 1989, 385 DOI: 10.1039/C39890000385

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements