Interaction site enthalpies of the phenol–tetrahydrofuran hydrogen-bond complex in various solvents

Abstract

Enthalpies of solution of several solutes in cyclohexane, benzene, toluene, p-xylene, carbon tetrachloride and 1,1,2,2-tetrachloroethane have been measured. They permitted a determination of the interaction site enthalpies of phenol (Ph) and tetrahydrofuran (THF) molecules with the solvents mentioned above. Spencer's additive model of solute–solvent interaction was used. These interaction site enthalpies were used to calculate the enthalpies of PH–THF complex formation [ΔH(complex)] and transfer enthalpies [ΔH^tr(complex)] of this complex from cyclohexane to other solvents used. A good agreement between the calculated and experimental values of ΔH(complex) and ΔH^tr(complex) shows the correctness of the simple model of molecular interactions being used.