A combined electrochemical process for the reageneration of co-enzymes

Abstract

Cyclic regeneration of the co-enzyme nicotinamide adenine dinucleotide couple NAD⁺/NADH has been achieved by reduction of NAD⁺ using electrochemically produced potassium amalgam in a specially designed reactor, and by electrochemically oxidising NADH and biochemically inactive species from the reduction reaction back to active NAD⁺via a nickel foam anode; this regenerated co-enzyme can be used to drive a range of chemical reactions catalysed by oxido–reductase enzymes.