Facile generation and trapping of α-oxo-o-quinodimethane; a synthesis of 3-aryl-3,4-dihydroisocoumarins
Abstract
Treatment of o-(trimethylsilylmethyl)benzoyl chloride (1) with fluoride ions in the presence of aromatic aldehydes and alkyl fumarates gives 3-aryl-3,4-dihydroisocoumarins (3) and substituted α-tetralones (4), respectively.