Synthesis of 7,13-bridged arachidonic acid analogues
Abstract
cis- and trans-7,13-Bridged arachidonic acids (2 and 3, RH) and their 5,6,14,15-tetradehydro-analogues (4 and 5, R
H) have been synthesized employing a divinylcyclopropane rearrangement as a key step.