An unexpected outcome of the reaction of a racemic carbapen-1-em with osmium(VIII) oxide
Abstract
t-Butyl 2-ethoxycarbonylcarbapen-1-em-3-exo-carboxylate (1a) reacts with osmium (VIII) oxide to give t-butyl (1SR,5SR,7RS,8RS)-1-ethoxycarbonyl-8-hydroxy-2-oxa-6-azabicyclo[3.2.1]octane-7-carboxylate (7a).