Synthesis of γ-aminobutyric acid analogues of restricted conformation. Part 2. The 2-(aminomethyl)cycloalkanecarboxylic acids
Abstract
The syntheses of analogues with restricted rotation about the C(2)–C(3) bond of γ-aminobutyric acid, namely cisand trans-2-(aminomethyl)-cyclopropane and -cyclobutanecarboxylic acids and trans-2-(aminomethyl)cyclohexanecarboxylic acid are described.