The syntheses of cis- and trans-2-aminocyclopropyl, -cyclobutyl, -cyclopentyl, and -cyclohexylacetic acids as γ-aminobutyric acid analogues of restricted conformation are described. Mass spectral evidence fully supports the stereochemical assignments of the configurational isomers.
P. D. Kennewell, S. S. Matharu, J. B. Taylor, R. Westwood and P. G. Sammes, J. Chem. Soc., Perkin Trans. 1, 1982, 2553 DOI: 10.1039/P19820002553
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