Haemin–acirdines intercalate into duplex DNA via the acridine moiety and, in the presence of reducing agents, cause oxygen dependent scission and show antileukemic properties analogous to the action of the glycopeptide antibiotic bleomycin.
J. W. Lown and A. V. Joshua, J. Chem. Soc., Chem. Commun., 1982, 1298 DOI: 10.1039/C39820001298
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