Nitroxide radicals. Part 20. Formation and reactions of t-butyl p-formylphenyl nitroxide and its derivatives

Abstract

Preparation of the parent hydroxylamine of the title nitroxide and its conversion into several hydroxylamine derivatives and the corresponding nitroxides has been achieved with a view to using functionalised aryl nitroxides as spin labels. The a_N values of the derived aryl nitroxides vary with the nature of their para-substituents, thus providing a potential method for identifying the site of attachment of aryl nitroxide spin labels.

Reactions of a nitrone-nitroxide, derived from the title radical, with cyanoisopropyl, phenyl, benzoyloxyl, and t-butoxyl radicals were investigated. In no case was a bisnitroxide formed.