Issue 5, 1981

Penicillin biosynthesis: conversion of deuteriated (L-α-amino-δ-adipyl)-L-cysteinyl-D-valine into isopenicillin N by a cell-free extract of Cephalosporium acremonium

Abstract

The tripeptide (L-α-amino-δ-adipyl)-L-cysteinyl-D-[22H, Me2–2H6]valine was converted into isopenicillin N by a cell-free extract ofCephalosporium acremonium;; complete retention of all deutrons was confirmed by 2H n.m.r. spectroscopy

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1981, 246-247

Penicillin biosynthesis: conversion of deuteriated (L-α-amino-δ-adipyl)-L-cysteinyl-D-valine into isopenicillin N by a cell-free extract of Cephalosporium acremonium

J. E. Baldwin, M. Jung, J. J. Usher, E. P. Abraham, J. A. Huddleston and R. L. White, J. Chem. Soc., Chem. Commun., 1981, 246 DOI: 10.1039/C39810000246

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