Issue 0, 1980

Bacteriostatic activity of fluoro-analogues of 5-(2-hydroxyethyl)-4-methylthiazole, a metabolic intermediate in the biosynthesis of thiamine

Abstract

2-Fluoro-5-(2-hydroxyethyl)-4-methylthiazole and 5-(2-fluoroethyl)-4-methylthiazole have been prepared and the latter converted into a fluoro-analogue of thiamine. All three compounds show bacteriostatic activity against E. coli.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1980, 2026-2028

Bacteriostatic activity of fluoro-analogues of 5-(2-hydroxyethyl)-4-methylthiazole, a metabolic intermediate in the biosynthesis of thiamine

G. Lowe and B. V. L. Potter, J. Chem. Soc., Perkin Trans. 1, 1980, 2026 DOI: 10.1039/P19800002026

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