Issue 15, 1980

A new method for the carbon-extension reactions of azetidin-2-ones at the 4-position

Abstract

High yields of 4-alkyl-, 4-allyl-, 4-vinyl-, or 4-ethynyl-azetidin-2-ones are obtained by treating 4-sulphonylazetidin-2-ones with either lithium organocuprates or Grignard reagents, but yields from 4-acetoxyazetidin-2-one with Grignard reagents are low.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1980, 736-737

A new method for the carbon-extension reactions of azetidin-2-ones at the 4-position

T. Kobayashi, N. Ishida and T. Hiraoka, J. Chem. Soc., Chem. Commun., 1980, 736 DOI: 10.1039/C39800000736

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