Issue 21, 1979

Nim-p-methoxyphenylsulphonylhistidine, a new derivative for peptide synthesis

Abstract

The p-methoxyphenylsulphonyl group attached at the Nim function of histidine can be quantitatively cleaved by trifluoroacetic acid in the presence of dimethyl sulphide at room temperature within 1 h; the Nim-tosyl group was also cleaved under similar conditions, but at a slower rate.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1979, 955-956

N im -p-methoxyphenylsulphonylhistidine, a new derivative for peptide synthesis

K. Kitagawa, K. Kitade, Y. Kiso, T. Akita, S. Funakoshi, N. Fujii and H. Yajima, J. Chem. Soc., Chem. Commun., 1979, 955 DOI: 10.1039/C39790000955

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