Issue 18, 1979

Asymmetric reduction of prochiral aromatic ketones with reagents prepared from sodium borohydride and Lewis acids in the presence of 1,2:5,6-di-O-iso-propylidene-α-D-glucofuranose

Abstract

Asymmetric reduction of aromatic ketones with reagents formed from sodium borohydride and various Lewis acids in the presence of 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose afforded the corresponding phenyl carbinols in reasonably good optical yields (up to 88%).

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1979, 807-808

Asymmetric reduction of prochiral aromatic ketones with reagents prepared from sodium borohydride and Lewis acids in the presence of 1,2:5,6-di-O-iso-propylidene-α-D-glucofuranose

A. Hirao, S. Nakahama, D. Mochizuki, S. Itsuno, M. Ohowa and N. Yamazaki, J. Chem. Soc., Chem. Commun., 1979, 807 DOI: 10.1039/C39790000807

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