Hydroxy-steroids. Part 21. The preparation and proton nuclear magnetic resonance spectra of 19-norergosta-3,5,7,9,22-pentaene and -3,5,7,9-tetraene, 7-methoxy-1,2-dihydronaphthalene, and deuteriated derivatives

Abstract

Efficient methods for the preparation of the compounds listed in the title have been developed. Examination of their ¹H n.m.r. spectra showed that in these substituted dihydronaphthalenes the ring containing the olefinic bond is conformationally mobile. Study of the deuteriated derivatives was useful in interpreting the gross spectrometric features of the parent compounds but did not simplify the detailed analysis.