Formation of inclusion complexes of benzophenone derivatives; β-cyclodextrin studied by induced circular dichroism

Abstract

Benzophenone derivatives form 1 : 1 inclusion complex with β-cyclodextrin, exhibiting an induced optical activity. The induced c.d. data arising from the n–π* electric transition of the carbonyl group indicate that complex formation is enhanced by hydrophobic substituents and is prevented by hydrophilic ones on the aromatic rings, and that the substituents often exert an influence on the structure of the inclusion complex.