Preparation of NN′-linked bi(heteroaryls) from dehydroacetic acid and 2,6-dimethyl-4-pyrone

Abstract

A number of novel NN′-linked bi(heteroaryls)(1) and their cations [(2) and (3)] have been prepared by the reaction of dehydroacetic acid (4) or 2,6-dimethyl-4-pyrone (5) with N-amino-heterocycles. Analogous reactions of simple hydrazines have also been investigated. In particular, the chemistry of 2,6-dimethyl-1-(1,2,4-triazol-4-yl)-4-pyridone (16) and related cationic species has been investigated in some detail.