Issue 11, 1977

Ene reaction of chloral with olefins catalysed by Lewis acids, and some applications in organic synthesis

Abstract

Chloral has been found to react with representative examples of mono-, 1,1-di-, and 1,2-di-alkylsubstituted ethylenes to afford ene adducts in synthetically useful yield, and under mild conditions, when a Lewis acid is employed in catalytic quantities to enhance the reaction rate; the usefulness of these reactions is demonstrated by various transformations of the 1-hydroxy-2,2,2-trichloroethyl unit.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1977, 380-382

Ene reaction of chloral with olefins catalysed by Lewis acids, and some applications in organic synthesis

G. B. Gill and B. Wallace, J. Chem. Soc., Chem. Commun., 1977, 380 DOI: 10.1039/C39770000380

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