Experiments with 13C2-labelled materials prove that the formation of uro'gen-III (6) from unrearranged AP·AP pyrromethane (2) by deaminase-cosynthetase is mechanistically equivalent to what was discovered earlier for porphobilinogen.
A. R. Battersby, D. W. Johnson, E. McDonald and D. C. Willimas, J. Chem. Soc., Chem. Commun., 1977, 117 DOI: 10.1039/C39770000117
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