The acidities of weak acids. Part IV. Some methyl styryl ketones

Abstract

A series of ring-substituted methyl styryl ketones (XC₆H₄·CH:CH·CO·CH₃) have been synthesised and their acidities measured at 298.2 K using solutions of tetramethylammonium hydroxide (0.011 M) in dimethyl sulphoxide–water mixtures. In most cases the rates of detritiation in aqueous hydroxide ion solutions have also been measured. The results show that these compounds obey the same pK_a–lgk^T_OH^– relationship as was established for the structurally similar acetophenones.