2-Aminopyrrolo[1,2-a]- and 3-aminopyrrolo[1,2-c]-pyrimidines
Abstract
Treatment of 4-amino-6-methylpyrimidine with phenacyl bromide followed by base gives 3-amino-6-phenyl-pyrrolo[1,2-c]pyrimidine and not 7-methyl-2-phenylmidazo[1,2-c]pyrimidine as reported previously. Similar treatment of 4-amino-2-methyl- and 4-amino-2,6-dimethyl-pyrimidine yields 2-amino-7-phenyl- and 2-amino-4-methyl-7-phenyl-pyrrolo[1,2-a]pyrimidine, respectively.