By use of tritium labelled substrates, and h.p.l.c., it is shown that protoporphyrin-IX (1d) is formed from coproporphyrinogen-III (2a)via a specific pathway involving harderoporphyrinogen (2b) rather than its isomer (2c).
D. E. Games, A. H. Jackson, J. R. Jackson, R. V. Belcher and S. G. Smith, J. Chem. Soc., Chem. Commun., 1976, 187 DOI: 10.1039/C39760000187
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