The von Auwers' boiling point rule. A new approach

Abstract

An empirical approach to the determination of relationships between b.p.s and chemical constitution in a homologous series of compounds is described. Molar volumes are shown to be similarly useful in structural and stereochemical studies. The relationships derived should be useful for predicting b.p.s and assignment of stereochemistry in several series of compounds. Large discrepancies between observed and predicted values in certain 1,3-dioxans are taken as indicators of twist conformations.