The synthesis of cis- and trans-2-methyl- and 2,NN-trimethylchroman-3-amines is described. Configurations and preferred conformations are assigned to the free bases, and to derivatives (hydrochlorides, N-acetyl, N-phthaloyl) by interpretation of proton magnetic resonance spectra recorded at 220 MHz.
H. Booth, D. Huckle and I. M. Lockhart, J. Chem. Soc., Perkin Trans. 2, 1973, 227 DOI: 10.1039/P29730000227
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