Synthesis and quaternization of some heterocyclic mono- and disulphides

Abstract

The synthesis of bis-(1-phenylimidazo[1,5-a]pyridin-3-yl) disulphide, its 3-phenyl 1,1′-linked analogue, bis-(2-phenylimidazo[1,2-a]pyridin-3-yl) disulphide, bis-(3-methyl-2-phenylindolizin-1-yl) disulphide, and bis-(α-2-pyridylbenzyl) disulphide is described, and also the synthesis of the corresponding 1- and 3-phenylimidazo[1,5-a]pyridine monosulphides. The action of methyl iodide and methyl fluorosulphonate on these mono- and disulphides is described, as is the action of alkali on the derived disulphide diquaternary salts.