Total synthesis of the alkloids (±)-oxocrinine and (±)-oxomaritidine via anodic oxidation
Abstract
(±)-Oxocrinine (5a) and (±)-oxomaritidine (5b) were synthesized by anodic oxidation of the trifluroacetyl derivatives of N-(4-methoxyphenethyl)-3,4-methylenedioxybenzylamine (3a) and N-(4-methoxyphenethyl)3,4-dimethoxybenzylamine (3b) followed by hydrolysis.