Optically active co-ordination compounds. Part XXIX. Resolution of 1,2,4-triglycinatocobalt(III) by a bacterial method and determination of its optical purity by isotope dilution

Abstract

1,2,4-[Co(gly-Ō)₃]†; has been partially resolved by stereoselective decomposition using Proteus vulgaris. Further resolution was achieved by fractional crystallisation from water. This sample was shown to be 99·8 ± 1·5% optically pure by the method of isotope dilution. The pure enantiomer therefore has Δε₅₃₅= 2·75 ± 0·05.