Mechanism of formation of benzimidazoles by oxidation of o-acylamino-NN-dialkylanilines with peroxy-acids
Abstract
The mechanism of the peroxy-acid-catalysed cyclisation of N-(o-acylaminophenyl)pyrrolidine (and related systems), which has been suggested to occur by way of an N-oxide intermediate, has been established by formation of such an N-oxide [N-(2-benzoylaminophenyl)pyrrolidine N-oxide] and its cyclisation under acidic conditions.