Reactivity of ethylenic compounds: bromination reaction. Solvation and charge development in the transition state of AdEC1 mechanism in hydroxylic solvents
Abstract
An analysis of the secondary solvent isotope effect and of the solvent effect in methanol–water mixtures on the rate of bromination of pent-1-ene indicates that the transition state for this reaction is highly polarized and essentially solvated through hydrogen bonding.