Automatic radiofrequency titration of acids in tertiary butyl alcohol-acetone medium

Abstract

The mixed solvent t-butyl alcohol-acetone can be used as a differentiating medium for the titration of acids with a standard solution of tetran-butylammonium hydroxide dissolved in a mixture of toluene and methanol. Titration curves of various shapes can be obtained and the simultaneous determination of certain acids achieved. The differences in curve shapes obtained by radiofrequency titration can be used as the basis of separation. The low toxicity of t-butyl alcohol (compared with other solvents at present in widespread use for the titration of weak acids) combined with its low solvating power and good differentiating properties make it a suitable medium for the routine determination of such acids in admixture.