Issue 3, 1970

New stereospecific routes to both epimers of 2-methyl-3-oxo- and 3-methyl-2-oxo-steroids via 2-lithio-1,3-dithian–epoxide reactions

Abstract

The potential of 2-lithio-1,3-dithian–epoxide reactions for the stereospecific substitution of the steroid skeleton in a desired position has been illustrated by their application in the preparation of both epimers of 2-methyl-3-oxo- and 3-methyl-2-oxo-5α-cholestane.

Article information

Article type
Paper

J. Chem. Soc. D, 1970, 141-142

New stereospecific routes to both epimers of 2-methyl-3-oxo- and 3-methyl-2-oxo-steroids via 2-lithio-1,3-dithian–epoxide reactions

J. B. Jones and R. Grayshan, J. Chem. Soc. D, 1970, 141 DOI: 10.1039/C29700000141

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