Issue 1112, 1968

Screening for alkaloids in toxicology by using thin-layer chromatography: a rapid system simulating paper chromatography

Abstract

Although numerous thin-layer chromatographic systems for the separation of alkaloids have been reported, none of them compares in abundance of recorded RF values with the citrate paper system of Curry and Powell. In order to overcome the slowness (which can be a serious disadvantage with this paper system in diagnosis of acute poisoning) without recourse to a new thin-layer chromatographic system and consequent sacrifice of results, a system has been developed that gives RF values which, for practical purposes, are substantially the same as those in the paper system, for the limited range of drugs examined and for their extracts from horse urine. It is unlikely that the correlation is due to chance, and it is considered, therefore, that the more rapid thin-layer chromatographic system can be substituted for the paper system.

Article information

Article type
Paper

Analyst, 1968,93, 737-739

Screening for alkaloids in toxicology by using thin-layer chromatography: a rapid system simulating paper chromatography

P. E. Haywood and M. S. Moss, Analyst, 1968, 93, 737 DOI: 10.1039/AN9689300737

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements