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Chapter 12

Developing the Applicability Domain of In Silico Models: Relevance, Importance and Methods

Given the problems and limitations of animal testing, the development and utilisation of in silico approaches to predict biological activity, toxicity and absorption, distribution, metabolism and excretion (ADME) endpoints continues to grow year on year. As introduced previously (Chapter 2), (quanti...
Print publication date: 28 Oct 2010
Copyright year: 2011
Print ISBN: 978-1-84973-004-4
PDF eISBN: 978-1-84973-209-3
From the book series:
Issues in Toxicology