Facile synthesis of Fe–baicalein nanoparticles for photothermal/chemodynamic therapy with accelerated FeIII/FeII conversion

Zhendong Liu; Chunling Hu; Sainan Liu; Lihan Cai; Ying Zhou; Maolin Pang

doi:10.1039/D1TB00200G

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Facile synthesis of Fe–baicalein nanoparticles for photothermal/chemodynamic therapy with accelerated Fe^III/Fe^II conversion†

Zhendong Liu,^ab Chunling Hu,

^ab Sainan Liu,

^ab Lihan Cai,^ab Ying Zhou^a and Maolin Pang

*^ab

Author affiliations

* Corresponding authors

^a State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Science, Changchun 130022, P. R. China
E-mail: mlpang@ciac.ac.cn

^b University of Science and Technology of China, Hefei 230026, P. R. China

Abstract

Fe²⁺–baicalein–polyethylene glycol (Fe–BaP) nanoparticles were synthesized by a room temperature wet chemical method via coordination between Fe²⁺ and baicalein. Fe–BaP possessed high photothermal conversion efficiency (η = 45.6%) and excellent antitumor efficacy was achieved with the synergistic photothermal/chemodynamic tumor therapy.

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Article information

DOI: https://doi.org/10.1039/D1TB00200G
Article type: Communication
Submitted: 31 Jan 2021
Accepted: 16 Mar 2021
First published: 27 Mar 2021

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J. Mater. Chem. B, 2021,9, 3295-3299

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Facile synthesis of Fe–baicalein nanoparticles for photothermal/chemodynamic therapy with accelerated Fe^III/Fe^II conversion

Z. Liu, C. Hu, S. Liu, L. Cai, Y. Zhou and M. Pang, J. Mater. Chem. B, 2021, 9, 3295 DOI: 10.1039/D1TB00200G

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Journal of Materials Chemistry B