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Issue 31, 2019
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A non-intrusive evaluation method for tumor-targeting characteristics of nanomedicines based on in vivo near-infrared fluorescence imaging

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Abstract

We developed a novel evaluation method for tumor-targeting characteristics of nanomedicines, average tumor-targeting index (average TTI) and “area under the tumor-targeting index-time curve” (AUTC) were established as the indicators for tumor targeting of nanomedicines based on NIR fluorescence imaging, which helps real-time monitoring of targeting ability and tumor changes in vivo without culling animals.

Graphical abstract: A non-intrusive evaluation method for tumor-targeting characteristics of nanomedicines based on in vivo near-infrared fluorescence imaging

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Article information


Submitted
04 May 2019
Accepted
11 Jul 2019
First published
15 Jul 2019

J. Mater. Chem. B, 2019,7, 4751-4757
Article type
Communication

A non-intrusive evaluation method for tumor-targeting characteristics of nanomedicines based on in vivo near-infrared fluorescence imaging

H. Liu, R. T. Marquez, X. Wu, K. Li, S. Vadlamani, S. Li, Y. Wang, L. Xu and D. Wu, J. Mater. Chem. B, 2019, 7, 4751
DOI: 10.1039/C9TB00882A

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