Issue 47, 2018

NIR-responsive carbon-based nanocarriers for switchable on/off drug release and synergistic cancer therapy

Abstract

Herein, we present a light-switchable drug delivery system based on chitosan-gated carbon-based nanocarriers (CGC NCs) that exhibit a loading capacity for doxorubicin as high as ∼89.65 wt% and controlled on/off release with/without NIR irradiation. In vitro and in vivo results show that the CGC NCs manifest high efficacy for cancer therapy through a synergistic effect of combined chemo-photothermal treatment.

Graphical abstract: NIR-responsive carbon-based nanocarriers for switchable on/off drug release and synergistic cancer therapy

Supplementary files

Article information

Article type
Communication
Submitted
11 Sep 2018
Accepted
23 Oct 2018
First published
25 Oct 2018

J. Mater. Chem. B, 2018,6, 7794-7799

NIR-responsive carbon-based nanocarriers for switchable on/off drug release and synergistic cancer therapy

R. Nie, H. Liu, L. Hu, X. Gu, J. Qian and H. Wang, J. Mater. Chem. B, 2018, 6, 7794 DOI: 10.1039/C8TB02398K

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