Issue 38, 2018
From the journal:

Journal of Materials Chemistry B

NIR fluorescent organic nanoparticles for photoinduced nitric oxide delivery with self monitoring and real time reporting abilities†

Krishna Kalyani Behara,a   Y. Rajesh,b   Amrita Chaudhuri,a   Moumita Gangopadhyay,a   Mahitosh Mandal*b  and  N. D. Pradeep Singh ORCID logo *a  

* Corresponding authors

a Department of Chemistry, Indian Institute of Technology (IIT) Kharagpur, Kharagpur–721302, India
E-mail: ndpradeep@chem.iitkgp.ernet.in

b School of Medical Science and Technology, Indian Institute of Technology Kharagpur, Kharagpur–721302, India

Abstract

Nitric oxide photodonor (NOD) conjugated perylene tetracarboxylate ester (TPT) based fluorescent organic TPT(NOD)4 nanoparticles (NPs) with aggregation induced NIR emission have shown photoinduced nitric oxide delivery along with a red to green emission transition. Time dependent imaging and dose dependent cytotoxicity studies of these NPs using U87MG cells demonstrate the self monitoring and real time reporting abilities and potential anticancer activity of the system, respectively.

Graphical abstract: NIR fluorescent organic nanoparticles for photoinduced nitric oxide delivery with self monitoring and real time reporting abilities

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Article information

DOI
https://doi.org/10.1039/C8TB01209A
Article type
Communication
Submitted
07 May 2018
Accepted
27 Aug 2018
First published
29 Aug 2018

J. Mater. Chem. B, 2018,6, 6042-6046

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NIR fluorescent organic nanoparticles for photoinduced nitric oxide delivery with self monitoring and real time reporting abilities

K. K. Behara, Y. Rajesh, A. Chaudhuri, M. Gangopadhyay, M. Mandal and N. D. Pradeep Singh, J. Mater. Chem. B, 2018, 6, 6042 DOI: 10.1039/C8TB01209A

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