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Issue 24, 2018
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Recent progress on graphene-based substrates for surface-enhanced Raman scattering applications

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Abstract

Since the intriguing and inspiring discovery of graphene-enhanced Raman scattering (GERS) in 2010, graphene and graphene-based substrates have attracted significant attention in both theoretical research and application exploration of surface-enhanced Raman scattering (SERS); this makes graphene-involved SERS a burgeoning area in many scientific branches. The introduction of graphene not only overcomes some intrinsic drawbacks of SERS, but also has a great synergistic effect with traditional noble metal nanoparticle enhancement substrates and thus greatly improves the sensing performance of SERS and largely expands its application area. To better learn about the recent progress in graphene-based SERS substrates and shed light on future research, an overview of graphene and graphene-based SERS substrates is presented herein. In this review, the role played by graphene in graphene-based SERS substrates is first summarized, and then, the classification and preparation methods of graphene-based substrates are presented, which are helpful for understanding the structure–property relationship. Furthermore, the SERS applications of graphene-based substrates in biomedical areas, including biomolecule detection, bio-imaging, cancer diagnosis and therapy and drug delivery, are highlighted. Other applications in hot-topic areas such as food safety and environmental monitoring are also briefly discussed. Finally, challenges and perspectives on the deficiencies, future development and achievements are presented.

Graphical abstract: Recent progress on graphene-based substrates for surface-enhanced Raman scattering applications

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Article information


Submitted
04 Apr 2018
Accepted
02 May 2018
First published
23 May 2018

J. Mater. Chem. B, 2018,6, 4008-4028
Article type
Review Article

Recent progress on graphene-based substrates for surface-enhanced Raman scattering applications

H. Lai, F. Xu, Y. Zhang and L. Wang, J. Mater. Chem. B, 2018, 6, 4008
DOI: 10.1039/C8TB00902C

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