Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 27th March 2019 from 11:00 AM to 1:00 PM (GMT).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 28, 2018
Previous Article Next Article

Aggregation-induced emission luminogen-based fluorescence detection of hypoxanthine: a probe for biomedical diagnosis of energy metabolism-related conditions

Author affiliations

Abstract

Hypoxanthine is a well-known indicator of intracellular energy status that is associated with many pathological conditions. We report a fluorescent luminogen (TPE-HPro) with aggregation-induced emission (AIE) feature which, along with xanthine oxidase (XO), detects and quantifies hypoxanthine in a “turn-on” manner. The superior detection performance of this fluorometric assay indicates its great potential for biomedical diagnostics.

Graphical abstract: Aggregation-induced emission luminogen-based fluorescence detection of hypoxanthine: a probe for biomedical diagnosis of energy metabolism-related conditions

Back to tab navigation

Supplementary files

Publication details

The article was received on 24 Mar 2018, accepted on 22 Jun 2018 and first published on 23 Jun 2018


Article type: Communication
DOI: 10.1039/C8TB00803E
Citation: J. Mater. Chem. B, 2018,6, 4575-4578

  •   Request permissions

    Aggregation-induced emission luminogen-based fluorescence detection of hypoxanthine: a probe for biomedical diagnosis of energy metabolism-related conditions

    Z. Zhang, R. T. K. Kwok, Y. Yu, B. Z. Tang and K. M. Ng, J. Mater. Chem. B, 2018, 6, 4575
    DOI: 10.1039/C8TB00803E

Search articles by author

Spotlight

Advertisements