Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 21st October 2020 from 07:00 AM to 07:00 PM (BST).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 38, 2017
Previous Article Next Article

2,3-Dialdehyde nanofibrillated cellulose as a potential material for the treatment of MRSA infection

Author affiliations

Abstract

Nanocellulose materials have undergone rapid development in recent years as promising biomedical materials due to their excellent physical and biological properties, in particular their biocompatibility, biodegradability, and low cytotoxicity. In this study, we prepared 2,3-dialdehyde nanofibrillated cellulose (DANFC) by sodium periodate oxidation, which is a mild oxidation process. With increasing oxidation time, the antimicrobial activity of DANFC against both Staphylococcus aureus (S. aureus) and methicillin-resistant Staphylococcus aureus (MRSA) improved. DANFC also displays good biocompatibility with mammalian cells, and shows good blood compatibility. In addition, animal studies and histology results reveal that DANFC can accelerate wound healing and enhance the formation of blood vessels and epithelium.

Graphical abstract: 2,3-Dialdehyde nanofibrillated cellulose as a potential material for the treatment of MRSA infection

Back to tab navigation

Supplementary files

Article information


Submitted
10 Jul 2017
Accepted
08 Sep 2017
First published
26 Sep 2017

J. Mater. Chem. B, 2017,5, 7876-7884
Article type
Paper

2,3-Dialdehyde nanofibrillated cellulose as a potential material for the treatment of MRSA infection

K. Mou, J. Li, Y. Wang, R. Cha and X. Jiang, J. Mater. Chem. B, 2017, 5, 7876
DOI: 10.1039/C7TB01857F

Social activity

Search articles by author

Spotlight

Advertisements