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Issue 20, 2017
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Photothermal triggered protein release from an injectable polycaprolactone-based microspherical depot

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Abstract

Upon exposure to visible light, controlled multiple dose protein release was demonstrated by using a microspherical depot composed of biodegradable poly(ε-caprolactone) (PCL), bovine serum albumin (BSA) or horseradish peroxidase (HRP) as model protein, polymer-coated gold nanoparticles as photothermal component, which can potentially reduce the number of invasive therapeutic injections.

Graphical abstract: Photothermal triggered protein release from an injectable polycaprolactone-based microspherical depot

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Article information


Submitted
27 Mar 2017
Accepted
08 May 2017
First published
10 May 2017

J. Mater. Chem. B, 2017,5, 3634-3639
Article type
Communication

Photothermal triggered protein release from an injectable polycaprolactone-based microspherical depot

C. Ge, J. S. Basuki, J. White, R. Hou, Y. Peng, T. C. Hughes and T. Tan, J. Mater. Chem. B, 2017, 5, 3634
DOI: 10.1039/C7TB00837F

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