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Issue 33, 2016
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An AIE-based bioprobe for differentiating the early and late stages of apoptosis mediated by H2O2

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Abstract

A bioprobe, TPE–Zn2BDPA, with aggregation-induced emission characteristics was designed and synthesized to differentiate the early and late stages of apoptosis mediated by H2O2. TPE–Zn2BDPA does not respond to healthy cells, but it selectively lights up the membrane of apopotic cells in both stages with brighter fluorescence in the late apoptotic stage.

Graphical abstract: An AIE-based bioprobe for differentiating the early and late stages of apoptosis mediated by H2O2

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Article information


Submitted
11 Jul 2016
Accepted
26 Jul 2016
First published
26 Jul 2016

J. Mater. Chem. B, 2016,4, 5510-5514
Article type
Communication

An AIE-based bioprobe for differentiating the early and late stages of apoptosis mediated by H2O2

A. C. S. Leung, E. Zhao, R. T. K. Kwok, J. W. Y. Lam, C. W. T. Leung, H. Deng and B. Z. Tang, J. Mater. Chem. B, 2016, 4, 5510
DOI: 10.1039/C6TB01734G

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