Jump to main content
Jump to site search

Issue 33, 2016
Previous Article Next Article

The preparation of organoboron-based stilbene nanoparticles for cell imaging

Author affiliations

Abstract

In this work, a series of nanoparticles were prepared assembled by a highly emissive solid-state organoboron-based stilbene (OBS) and PS-PEG-COOH via regulating the ratio of these two compounds using a co-precipitation method. The resultant OBS nanoparticles (OBSNs) were homogeneously dispersed in water media with average sizes of 36–82 nm and exhibited large Stokes shift, high fluorescence quantum yield, excellent photostability and low cytotoxicity. These organic nanoparticles could be internalized by MCF-7 cells and could accumulate in the cytoplasm outside the organelles. In addition, it is found that the nanoparticles with least negative charge and moderate size are most easily internalized by cells. Furthermore, the internalized nanoparticles could be retained inside the live cells for a long time and could be uniformly separated into two cells after the cell division process, permitting long-term cellular imaging applications.

Graphical abstract: The preparation of organoboron-based stilbene nanoparticles for cell imaging

Back to tab navigation

Supplementary files

Article information


Submitted
13 May 2016
Accepted
02 Aug 2016
First published
02 Aug 2016

J. Mater. Chem. B, 2016,4, 5515-5518
Article type
Communication

The preparation of organoboron-based stilbene nanoparticles for cell imaging

H. Yuan, L. Wang, S. Li, H. Liang, C. Lu, Y. Wang and C. Zhao, J. Mater. Chem. B, 2016, 4, 5515
DOI: 10.1039/C6TB01208F

Social activity

Search articles by author

Spotlight

Advertisements