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Issue 29, 2016
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Ultrasensitive ELISA+ enhanced by dendritic mesoporous silica nanoparticles

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Abstract

An ultrasensitive enzyme-linked immunosorbent assay (ELISA+) has been developed by using dendritic mesoporous silica nanoparticles (DMSNs) with high horseradish peroxidase (HRP) loading and easily accessible pore channels for signal amplification. A 2000 times enhancement of detection sensitivity compared to a commercial ELISA kit for insulin detection in serum is achieved.

Graphical abstract: Ultrasensitive ELISA+ enhanced by dendritic mesoporous silica nanoparticles

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Publication details

The article was received on 24 Apr 2016, accepted on 27 Jun 2016 and first published on 28 Jun 2016


Article type: Communication
DOI: 10.1039/C6TB01023G
J. Mater. Chem. B, 2016,4, 4975-4979

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    Ultrasensitive ELISA+ enhanced by dendritic mesoporous silica nanoparticles

    C. Lei, C. Xu, A. Nouwens and C. Yu, J. Mater. Chem. B, 2016, 4, 4975
    DOI: 10.1039/C6TB01023G

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