Issue 12, 2016

Layered MoS2 nanoflowers for microwave thermal therapy

Abstract

Microwave (MW) hyperthermia has received great attention as an emerging green tumor thermotherapy. In this work, layered MoS2 nanoflowers were prepared through a simple bottom-up hydrothermal process. By coating MoS2 nanoflowers with bovine serum albumin (BSA-MoS2), BSA-MoS2 exhibits low biotoxicity and excellent microwave susceptive properties in vitro. Meanwhile, the heating effect improvement by the layered structure was confirmed via a computer-simulated experiment. Finally, layered BSA-MoS2 nanoflowers are designed as MW hyperthermia susceptible agents for in vivo cancer therapy with 100% tumor elimination via MW irradiation at 1.8 W, 450 MHz.

Graphical abstract: Layered MoS2 nanoflowers for microwave thermal therapy

Supplementary files

Article information

Article type
Paper
Submitted
03 Feb 2016
Accepted
17 Feb 2016
First published
17 Feb 2016

J. Mater. Chem. B, 2016,4, 2133-2141

Layered MoS2 nanoflowers for microwave thermal therapy

S. Wang, L. Tan, P. Liang, T. Liu, J. Wang, C. Fu, J. Yu, J. Dou, H. Li and X. Meng, J. Mater. Chem. B, 2016, 4, 2133 DOI: 10.1039/C6TB00296J

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