Jump to main content
Jump to site search

Issue 17, 2016
Previous Article Next Article

A self-assembled lysinated perylene diimide film as a multifunctional material for neural interfacing

Author affiliations

Abstract

We report the design, synthesis and structure–property investigation of a new perylene diimide material (PDI-Lys) bearing lysine end substituents. Water processed films of PDI-Lys were prepared and their self-assembly, morphology and electrical properties in both inert and air environments were theoretically and experimentally investigated. With the aim of evaluating the potential of PDI-Lys as a biocompatible and functional neural interface for organic bioelectronic applications, its electrochemical impedance as well as the adhesion and viability properties of primary neurons on the PDI-Lys films were studied. By combining theoretical calculations and electrical measurements we show that due to conversion between neutral and zwitterionic anions, the PDI-Lys film conductivity increased significantly upon passing from air to an inert atmosphere, reaching a maximum value of 6.3 S m−1. We also show that the PDI-Lys film allows neural cell adhesion and neuron differentiation and decreases up to 5 times the electrode/solution impedance in comparison to a naked gold electrode. The present study introduces an innovative, water processable conductive film usable in organic electronics and as a putative neural interface.

Graphical abstract: A self-assembled lysinated perylene diimide film as a multifunctional material for neural interfacing

Back to tab navigation

Supplementary files

Article information


Submitted
03 Nov 2015
Accepted
22 Mar 2016
First published
23 Mar 2016

J. Mater. Chem. B, 2016,4, 2921-2932
Article type
Paper
Author version available

A self-assembled lysinated perylene diimide film as a multifunctional material for neural interfacing

S. Bonetti, M. Prosa, A. Pistone, L. Favaretto, A. Sagnella, I. Grisin, M. Zambianchi, S. Karges, A. Lorenzoni, T. Posati, R. Zamboni, N. Camaioni, F. Mercuri, M. Muccini, M. Melucci and V. Benfenati, J. Mater. Chem. B, 2016, 4, 2921
DOI: 10.1039/C5TB02299A

Social activity

Search articles by author

Spotlight

Advertisements