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Issue 38, 2015
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High-efficiency immunoassay platforms with controllable surface roughness and oriented antibody immobilization

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Abstract

High-efficiency immunoassay platforms with controlled surface roughness (single- and dual-scale structured surface) were prepared by combining a facile layer-by-layer particle deposition approach with oriented immobilization of antibodies through boronic acid moieties. The as-prepared surfaces showed significantly enhanced antibody loading capacity and antigen recognition, as proved by fluorescence images.

Graphical abstract: High-efficiency immunoassay platforms with controllable surface roughness and oriented antibody immobilization

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Publication details

The article was received on 17 Jun 2015, accepted on 07 Sep 2015 and first published on 09 Sep 2015


Article type: Communication
DOI: 10.1039/C5TB01164G
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J. Mater. Chem. B, 2015,3, 7499-7502

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    High-efficiency immunoassay platforms with controllable surface roughness and oriented antibody immobilization

    L. Song, J. Zhao, S. Luan, J. Ma, W. Ming and J. Yin, J. Mater. Chem. B, 2015, 3, 7499
    DOI: 10.1039/C5TB01164G

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